DNA Sequencing
Innovative Biotechnology that Shapes the World.

Exome Capture

Exome Capture

Service Description

Our Human Exome Prep and Sequencing service includes library prep, exome enrichment with Twist Exome 2.0, and sequencing to achieve ~30x coverage of the targeted regions per sample. The service is provided per batch of 12 samples. While the cost isn’t pro-rated for sample batches <12, the sequencing allotted to a batch stays consistent if the batches <12.

Advantages

Exome sequencing reduces the cost of sequencing the human genome by focusing on just the coding regions, or exons. By pooling 12 libraries prior to exome enrichment, we reduce the total number of enrichment reactions and significantly decrease costs.

Why should I choose exome sequencing instead of whole genome sequencing?

Whole genome sequencing (WGS) provides coverage of the entire genome (exons, introns, and mitochondrial DNA). WGS can result in a lot of data, some of which may be irrelevant to your research. Exome sequencing allows researchers to narrow in on specific genic regions of the genome at a much reduced cost. The sequencing cost savings can be translated to a more powerful experiment with a larger data set or used for other endeavors.

Access our Interactive Submission Guidelines and get the exact guidance you need to prepare, label, and deliver your samples.

 

If you can’t find the information you’re looking for, please contact us at nextgen-seq@biotech.wisc.edu

Human Exome Pricing

Effective 8/1/23

* Please inquire for sequencing specifications.

Prices are subject to change without notice. Please email nextgen-seq@biotech.wisc.edu to request a quote. In the absence of a valid quote, prices from our current price books will be applied at the time of the service request. Prices may differ from those listed on this page.

Unless otherwise specified, all data and reagents distributed by the University of Wisconsin Biotechnology Center DNA Sequencing Facility are intended for research purposes only. They are not intended nor certified for diagnostic or clinical use. Clinical services are provided through our collaboration with the UW Collaborative Genomics Core.